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TITLE Embryonic Stem Cell-Derived Therapies Targeting Cardiac Ischemic Disease ABSTRACT Cardiovascular disease (CVD) is the leading cause of death in the United States. Over one million Americans will suffer from a new or recurrent heart attacks this year and over 40 percent of those will die suddenly. In addition, about two-thirds of the patients develop congestive heart failure; and in people diagnosed with CHF, sudden cardiac death occurs at 6-9 times the general population rate. Heart transplantation remains the only viable solution for severely injured hearts; however, this treatment is limited by the availability of donor hearts. Therefore, alternative strategies to treat end stage heart failure and blocked blood vessels are needed.
PI Randall Lee INSTITUTE University of California, San Francisco STATE California AMOUNT $2,524,620.00 AWARD DATE 2007 March GRANT TYPE Comprehensive